Crosley CRSH268MW2 Bedienungsanleitung PDF herunterladen (Seite 63)

5 Discussion

BT3.

Remarkably SUPRA led to the identiﬁcation of 39 immunogenic proteins within the ACW-

proteins of S. aureus. The results obtained to date conﬁrmed the efﬁcacy of SUPRA in the

identiﬁcation of potential vaccine candidates. The gradual characterisation of the remaining

candidates will further increase the number of protective candidates for a multicomponent

vaccine. Combined with other components like IsdA and IsdB as well as the bivalent CP5-

CP8 conjugate a highly protective vaccine against S. aureus could be feasible. Additionally,

the generation of monoclonal antibodies for the most promising candidates like thus far BT1

and BT3 is a deﬁnite future objective, to analyse for the protective potential upon passive

immunisation.

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Crosley CRSH268MW2 Bedienungsanleitung Seite 63